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Preliminary results suggested exoASO-STAT6 administration had tumor growth inhibitory effects, greater than 90%, and 5080% complete remissions in colorectal cancer (CRC) and HCC models with minimal side effects [209]

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In consultation with the clinical experts, no major concern with the generalizability of results due to this difference was identified

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The findings suggest that substitution with Aib or Gly can fully prevent DPP-4 degradation